Hear from Professor Dawn Chandler on Ribonucleic Acid.
Professor Chandler’s research is centered on understanding the regulation of alternative pre-mRNA splicing and how disruption of this highly regulated process leads to diseases like cancer and spinal muscular atrophy. Her team is developing in vitro and animal model systems that can be used to create novel therapies targeting these disrupted pathways. The increased awareness of regulated RNA processing and the recent identification of several disease-causing mutations that affect splicing gives rise to a new generation of potential beneficial targets.
About the speaker
Professor Dawn Chandler is an Associate Professor in the Department of Pediatrics at The Ohio State University College of Medicine in Columbus, Ohio, and a Principal Investigator in the Center for Childhood Cancer and Blood Diseases at Abigail Wexner Research Institute at Nationwide Children’s Hospital. She received her Ph.D. from the University of Texas Graduate School of Biomedical Sciences at Houston and the University of Texas MD Anderson Cancer Center. Her research has been published in numerous high-impact journals, including Cancer Cell, Oncogene, and Cancer Research.