Dr Shona Wilson
Lucy Cavendish Fellow and University Lecturer in the Department of Pathology, Dr Wilson leads a multi-disciplinary consortium of eight partners researching liver fibrosis (caused by the parasitic worm Schistosoma mansoni) in Ugandan children. This four-year project, funded by the European & Developing Countries Clinical Trial Partnership (EDCTP) includes three Ugandan institutions. The debilitating, sometimes fatal schistosomiasis infection chronically afflicts some 200 million people in many of the world’s poorest countries. It is designated by the WHO as one of the world’s ‘great neglected diseases’ and a ‘disease of poverty’. The worms develop and live in the human blood stream for many years, releasing thousands of tissue-damaging eggs. Effective drug treatment is available, but in schistosomiasis endemic areas, reinfection occurs rapidly after treatment, especially in children. Shona is investigating the societal and biological causes, mechanisms and optimal disease control of liver fibrosis, caused by Schistosoma mansoni. Her research findings will provide information that is essential to combating this and other major parasitic health challenges in both the developed and developing world.